PROSPECTS FOR CREATING RADON CONTAINING AGENTS IN RADIONUCLIDE THERAPY

One of the methods for treating oncological diseases is application short-lived radionuclides. Existing risks intoxication and radioactive contamination can be eliminated by introduction a radon isotope into hard strong fullerene coat. To increase effectiveness these drugs it promising to introduce structural fragments amino acids, peptides, steroid hormones, nucleic bases or heterocyclic compounds being able accumulate exactly in tumoral but not healthy tissues body. The article presents data on quantum-chemical simulation electronic structure thermodynamic stability fullerenol radon-containing agents radionuclide therapy example model cortisonefullerenol bioconjugate.